![]() A current strategy that attempts to address this issue is the use of donor grafts that, up to approximately 15 years ago, would have been considered unfit for transplantation. The disparity between the number of candidates for liver transplantation and the number of potential donors is a worldwide issue. D-mElD scores were unable to predict survival in this cohort of Brazilian liver transplant recipients. Analysis of Kaplan-Meier curves for groups with D-MELD scores < 1,600 and ≥ 1,600 did not show statistically significant differences in survival (p = 0.722).Ĭonclusion. The c-statistic value for 1- and 3-month mortality was < 0.5 for the D-MELD. Overall survival at 1 and 3 months was 83.6%. Mean MELD and D-MELD scores were 16.3 ± 7.1 and 733.1 ± 437.8 respectively. Mean donor age was 44.9 ± 16.8 years (19.3% of donors were aged ≥ 60 years). Most recipients were male, with a mean age of 54.3 ± 9.6 years (n = 233 transplants). The Kaplan-Meier method was used to analyze survival as a function of time regarding D-MELD scores, and the Cox model was employed to assess the association between D-MELD and mortality. Receiver operating characteristic c-statistics were used to determine the ability of the D-MELD score to predict mortality. The main objective of the present study was to assess the predictive value of the D-MELD score for 1-month and 3-month post-transplant mortality in a cohort of patients who underwent deceased-donor liver transplantation in Southern Brazil. The D-MELD score was designed to prevent donor-recipient matches with a high risk of unfavorable outcome. Our journal seeks to publish articles on basic clinical care and translational research focused on preventing rather than treating the complications of end-stage liver disease. Topics covered by AoH include alcoholic liver disease, autoimmune hepatitis, biliary diseases, drug-induced liver injury, genetic liver diseases, NAFLD/NASH and viral hepatitis (HAV, HBV, HCV, HDV, HEV). AoH publishes editorials, opinions, concise reviews, original articles, brief reports, letters to the editor, news from affiliated associations, clinical practice guidelines and summaries of congresses in the field of Hepatology. It is the official journal of the Mexican Association of Hepatology ( AMH), the Latin American Association for the Study of the Liver ( ALEH), the Canadian Association for the Study of the Liver ( CASL) and the Czech Society of Hepatology ( CSH). Annals of Hepatology (AoH) is an international, open access journal published bi-monthly with funds from the Fundación Clínica Médica Sur. ![]()
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